Preclinical Studies of Chiauranib Show It Inhibits Transformed Follicular Lymphoma through the VEGFR2/ERK/STAT3 Signaling Pathway

• Main Authors: Yuanfang Tang (Author), Mengya Zhong (Author), Guangchao Pan (Author), Jinshui Tan (Author), Chendi Xie (Author), Yuelong Jiang (Author), Jingwei Yao (Author), Weihang Shan (Author), Jiaqi Lin (Author), Jiewen Huang (Author), Yating Liu (Author), Zhifeng Li (Author), Bing Xu (Author), Jie Zha (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transformed follicular lymphoma (t-FL), for which there is no efficient treatment strategy, has a rapid progression, treatment resistance, and poor prognosis, which are the main reasons for FL treatment failure. In this study, we identified a promising therapeutic approach with chiauranib, a novel o...