Activation of α7nAChR Protects Against Gastric Inflammation and Dysmotility in Parkinson's Disease Rats

• Main Authors: Li Zhou (Author), Li-Fei Zheng (Author), Xiao-Li Zhang (Author), Zhi-Yong Wang (Author), Yuan-Sheng Yao (Author), Xiao-Lin Xiu (Author), Chen-Zhe Liu (Author), Yue Zhang (Author), Xiao-Yan Feng (Author), Jin-Xia Zhu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cholinergic anti-inflammatory pathway (CAIP) has been proposed to regulate gastrointestinal inflammation via acetylcholine released from the vagus nerve activating α7 nicotinic receptor (α7nAChR) on macrophages. Parkinson's disease (PD) patients and PD rats with substantia nigra (SN) lesion...