Toll-like receptor 4 mutation mitigates gut microbiota-mediated hypertensive kidney injury

• Main Authors: Suravi Majumder (Author), Sathnur B. Pushpakumar (Author), Hebah Almarshood (Author), Rosemary Ouseph (Author), Dibson D. Gondim (Author), Venkatakrishna R. Jala (Author), Utpal Sen (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypertension-associated dysbiosis is linked to several clinical complications, including inflammation and possible kidney dysfunction. Inflammation and TLR4 activation during hypertension result from gut dysbiosis-related impairment of intestinal integrity. However, the contribution of TLR4 in kidne...