Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis.

• Main Authors: Fabiola Martin (Author), Hannah Castro (Author), Carolyn Gabriel (Author), Adine Adonis (Author), Alexandra Fedina (Author), Linda Harrison (Author), Liz Brodnicki (Author), Maria A Demontis (Author), Abdel G Babiker (Author), Jonathan N Weber (Author), Charles R M Bangham (Author), Graham P Taylor (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) become progressively impaired, with chronic pain, immobility and bladder, bowel and sexual dysfunction. Tested antiretroviral therapies have not been effective and most patients are offered a short course of corticoste...