The Antitumoral/Antimetastatic Action of the Flavonoid Brachydin A in Metastatic Prostate Tumor Spheroids In Vitro Is Mediated by (Parthanatos) PARP-Related Cell Death

• Main Authors: Diego Luis Ribeiro (Author), Katiuska Tuttis (Author), Larissa Cristina Bastos de Oliveira (Author), Juliana Mara Serpeloni (Author), Izabela Natalia Faria Gomes (Author), André van Helvoort Lengert (Author), Cláudia Quintino da Rocha (Author), Rui Manuel Reis (Author), Ilce Mara de Syllos Cólus (Author), Lusânia Maria Greggi Antunes (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metastatic prostate cancer (mPCa) is resistant to several chemotherapeutic agents. Brachydin A (BrA), a glycosylated flavonoid extracted from <i>Fridericia platyphylla</i>, displays a remarkable antitumoral effect against in vitro mPCa cells cultured as bidimensional (2D) monolayers. Con...