Cover Image

Rhodium-Catalyzed Ortho-Vinylation of 2-Arylpyridines and Its Application in the Total Synthesis of Palmatine

An efficient protocol by Rh-catalyzed direct C-H vinylation of 2-arylpyridines with a commercially available and air-stable potassium vinyl donor has been developed. This method affords the corresponding pyridinyl styrene derivative with moderate to excellent yields under mild conditions, which is e...

Full description

Saved in:
Bibliographic Details
Main Authors: Shan Lv (Author), Ruifang Nie (Author), Lingmei Guo (Author), Yang Zheng (Author), Yanzhao Liu (Author), Li Guo (Author), Yong Wu (Author)
Format: Book
Published: Georg Thieme Verlag KG, 2020-06-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An efficient protocol by Rh-catalyzed direct C-H vinylation of 2-arylpyridines with a commercially available and air-stable potassium vinyl donor has been developed. This method affords the corresponding pyridinyl styrene derivative with moderate to excellent yields under mild conditions, which is extremely beneficial to the total synthesis of the natural product palmatine.
Item Description:2628-5088
2628-5096
10.1055/s-0040-1712998

Similar Items