Intradermal DNA vaccine delivery using vacuum-controlled, needle-free electroporation

• Main Authors: Alison Generotti (Author), Ryne Contreras (Author), Brenden Zounes (Author), Eric Schade (Author), Andrea Kemme (Author), Yatish Rane (Author), Xinggang Liu (Author), Dustin Elwood (Author), Katherine Schultheis (Author), Jeremy Marston (Author), Jay McCoy (Author), Kate Broderick (Author), Paul Fisher (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Intradermal delivery of DNA vaccines via electroporation (ID-EP) has shown clinical promise, but the use of needle electrodes is typically required to achieve consistent results. Here, delivery of a DNA vaccine targeting the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is achieved using n...