Serum Extracellular Vesicle-Derived circHIPK3 and circSMARCA5 Are Two Novel Diagnostic Biomarkers for Glioblastoma Multiforme

• Main Authors: Michele Stella (Author), Luca Falzone (Author), Angela Caponnetto (Author), Giuseppe Gattuso (Author), Cristina Barbagallo (Author), Rosalia Battaglia (Author), Federica Mirabella (Author), Giuseppe Broggi (Author), Roberto Altieri (Author), Francesco Certo (Author), Rosario Caltabiano (Author), Giuseppe Maria Vincenzo Barbagallo (Author), Paolo Musumeci (Author), Marco Ragusa (Author), Cinzia Di Pietro (Author), Massimo Libra (Author), Michele Purrello (Author), Davide Barbagallo (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma multiforme (GBM) is the most frequent and deadly human brain cancer. Early diagnosis through non-invasive biomarkers may render GBM more easily treatable, improving the prognosis of this currently incurable disease. We suggest the use of serum extracellular vesicle (sEV)-derived circula...