Severe Multi-Resistant Pemphigus vulgaris: prolonged remission with a single cycle of Rituximab

• Main Authors: Isabela Soubhia Corral (Author), Thais Helena Proença de Freitas (Author), Renata Telles Rudge de Aquino (Author), Daniella Abbruzzini S. Koller (Author), Maria Elisa Ruffolo Magliari (Author), Helena Muller (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia, 2013-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pemphigus vulgaris is an autoimmune bullous disease whose therapy is based on systemic corticosteroids, with or without immunosuppressants. Rituximab is a chimeric monoclonal antibody of the IgG class, directed at a specific CD20 B cell surface antigen, used in pemphigus vulgaris empirically since 2...