Tumour necrosis factor-α mediates blood-brain barrier damage in HIV-1 infection of the central nervous system

Tumour necrosis factor-α mediates blood-brain barrier damage in HIV-1 infection of the central nervous system

The pathogenesis of brain inflammation and damage by human immunodeficiency virus (HIV) infection is unclear. Because blood-brain barrier damage and impaired cerebral perfusion are common features of HIV-1 infection, we evaluated the role of tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β...

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Bibliographic Details
Main Authors: M. K. Sharief (Author), M. Ciardi (Author), E. J. Thompson (Author), F. Sorice (Author), F. Rossi (Author), V. Vullo (Author), A. Cirelli (Author)
Format: Book
Published: Hindawi Limited, 1992-01-01T00:00:00Z.
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