Human Heme Oxygenase-1 Induced by Interleukin-6 via JAK/STAT3 Pathways Is a Tumor Suppressor Gene in Hepatoma Cells

• Main Authors: Kun-Chun Chiang (Author), Kang-Shuo Chang (Author), Shu-Yuan Hsu (Author), Hsin-Ching Sung (Author), Tsui-Hsia Feng (Author), Mei Chao (Author), Horng-Heng Juang (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Heme oxygenase-1 (HO-1) has several important roles in hepatocytes in terms of anti-inflammation, anti-apoptosis, and antioxidant properties. Interleukin-6 (IL-6) is a pleiotropic cytokine associated with liver regeneration and protection against injury. The aim of this study was to determine the po...