Design of an L-Valine-Modified Nanomicelle-Based Drug Delivery System for Overcoming Ocular Surface Barriers
The incidence of ocular surface disease (OSD) is increasing, with a trend towards younger ages. However, it is difficult for drugs to reach the deep layers of the cornea due to ocular surface barriers, and bioavailability is less than 5%. In this study, DSPE-PEG2000 was modified with L-valine (L-Val...
Saved in:
Main Authors: | Huimin Wu (Author), Yuchen Xu (Author), Mengru Cai (Author), Longtai You (Author), Jing Liu (Author), Xiaoxv Dong (Author), Xingbin Yin (Author), Jian Ni (Author), Changhai Qu (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Construction of a Multifunctional Nano-Scale Metal-Organic Framework-Based Drug Delivery System for Targeted Cancer Therapy
by: Mengru Cai, et al.
Published: (2021) -
Metal Organic Frameworks as Drug Targeting Delivery Vehicles in the Treatment of Cancer
by: Mengru Cai, et al.
Published: (2020) -
Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells via the Activation of Keap1/Nrf2/ARE Pathway
by: Hulinyue Peng, et al.
Published: (2022) -
Triptolide Induces Apoptosis Through Fas Death and Mitochondrial Pathways in HepaRG Cell Line
by: Longtai You, et al.
Published: (2018) -
Pharmacology, toxicity and pharmacokinetics of acetylshikonin: a review
by: Zhiqin Zhang, et al.
Published: (2020)