Modulating Neuro-Immune-Induced Macrophage Polarization With Topiramate Attenuates Experimental Abdominal Aortic Aneurysm

• Main Authors: Xing Chen (Author), Yang Li (Author), Jie Xiao (Author), Hua Zhang (Author), Chuanlei Yang (Author), Zhanjie Wei (Author), Weiqiang Chen (Author), Xinling Du (Author), Jinping Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development of abdominal aortic aneurysm (AAA) is attributed to psychological and physical factors. Topiramate, which is an agonist of the GABAA receptor, makes contributions to neuronal disease and is partially involved in immune regulation, may be effective upon abdominal aortic aneurysm progr...