Development and Application of a Dissolution-Transfer-Partitioning System (DTPS) for Biopharmaceutical Drug Characterization

• Päätekijät: Christian Jede (Tekijä), Laura J. Henze (Tekijä), Kirstin Meiners (Tekijä), Malte Bogdahn (Tekijä), Marcel Wedel (Tekijä), Valeria van Axel (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-03-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

A variety of in vitro dissolution and gastrointestinal transfer models have been developed aiming to predict drug supersaturation and precipitation. Further, biphasic, one-vessel in vitro systems are increasingly applied to simulate drug absorption in vitro. However, to date, there is a lack of comb...