Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues

• Main Authors: Lai Xu (Author), Helen Luo (Author), Rong Wang (Author), Wells W. Wu (Author), Je-Nie Phue (Author), Rong-Fong Shen (Author), Hartmut Juhl (Author), Leihong Wu (Author), Wei-lun Alterovitz (Author), Vahan Simonyan (Author), Lorraine Pelosof (Author), Amy S. Rosenberg (Author)
• Format: Book
• Published: BMC, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Reference genes are often interchangeably called housekeeping genes due to 1) the essential cellular functions their proteins provide and 2) their constitutive expression across a range of normal and pathophysiological conditions. However, given the proliferative drive of maligna...