Activation of the innate immune response against DENV in normal non-transformed human fibroblasts.

• Main Authors: José Bustos-Arriaga (Author), Jazmín García-Machorro (Author), Moisés León-Juárez (Author), Julio García-Cordero (Author), Leopoldo Santos-Argumedo (Author), Leopoldo Flores-Romo (Author), A René Méndez-Cruz (Author), Francisco J Juárez-Delgado (Author), Leticia Cedillo-Barrón (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>When mosquitoes infected with DENV are feeding, the proboscis must traverse the epidermis several times ("probing") before reaching a blood vessel in the dermis. During this process, the salivary glands release the virus, which is likely to interact first wit...