Modeling human T1D-associated autoimmune processesBox 1. Potential applications of models to understand the immune processes leading to human T1D.Box 2. Potential applications of models to evaluate treatments for human T1D.

• Үндсэн зохиолчид: Mohsen Khosravi-Maharlooei (Зохиогч), Rachel Madley (Зохиогч), Chiara Borsotti (Зохиогч), Leonardo M.R. Ferreira (Зохиогч), Robert C. Sharp (Зохиогч), Michael A. Brehm (Зохиогч), Dale L. Greiner (Зохиогч), Audrey V. Parent (Зохиогч), Mark S. Anderson (Зохиогч), Megan Sykes (Зохиогч), Remi J. Creusot (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Elsevier, 2022-02-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Background: Type 1 diabetes (T1D) is an autoimmune disease characterized by impaired immune tolerance to β-cell antigens and progressive destruction of insulin-producing β-cells. Animal models have provided valuable insights for understanding the etiology and pathogenesis of this disease, but they f...