Phenotypic diversity in beta-HbE thalassemia patients

• Main Authors: Pustika Amalia Wahidiyat (Author), Djajadiman Gatot (Author), Tenny Tjitrasari (Author), Harapan Parlindungan Ringoringo (Author), N S Marzuki (Author), R A Taufani (Author), I Setianingsih (Author), A Harahap (Author)
• Format: Book
• Published: Indonesian Pediatric Society Publishing House, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Thalassemia is a monogenic disease, yet the clini- cal manifestations (phenotype) are variable although they have the same genotype. The clear-cut correlation between genotype and phenotype in β-thalassaemia/HbE patients remains unex- plained. There are several factors that play a role in...