Effects of antihistamine on up-regulation of histamine H1 receptor mRNA in the nasal mucosa of patients with pollinosis induced by controlled cedar pollen challenge in an environmental exposure unit

• Main Authors: Yoshiaki Kitamura (Author), Hideyuki Nakagawa (Author), Tatsuya Fujii (Author), Takema Sakoda (Author), Tadao Enomoto (Author), Hiroyuki Mizuguchi (Author), Hiroyuki Fukui (Author), Noriaki Takeda (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, we examined the effects of antihistamine on the up-regulation of H1R mRNA in the nasal mucosa of patients with pollinosis induced by controlled exposure to pollen using an environmental exposure unit. Out of 20 patients, we designated 14 responders, whose levels of H1R mRNA in...