Cellular crosstalk of macrophages and therapeutic implications in non-small cell lung cancer revealed by integrative inference of single-cell transcriptomics

• Main Authors: Lei Wu (Author), Wenying Xia (Author), Yiting Hua (Author), Kun Fan (Author), Yanfei Lu (Author), Min Wang (Author), Yuexinzi Jin (Author), Wei Zhang (Author), Shiyang Pan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Non-small cell lung cancer (NSCLC) exhibits heterogeneity with diverse immune cell infiltration patterns that can influence tumor cell behavior and immunotherapy. A comprehensive characterization of the tumor microenvironment can guide precision medicine.Methods: Here, we generated a s...