Corticosterone as a Potential Confounding Factor in Delineating Mechanisms Underlying Ketamine's Rapid Antidepressant Actions

• Main Authors: Lauren Wegman-Points (Author), Brock Pope (Author), Allison Zobel-Mask (Author), Lori Winter (Author), Eric Wauson (Author), Vanja Duric (Author), Li-Lian Yuan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent research into the rapid antidepressant effect of subanesthetic doses of ketamine have identified a series of relevant protein cascades activated within hours of administration. Prior to, or concurrent with, these activation cascades, ketamine treatment generates dissociative and psychotomimet...