Imipramine is an orally active drug against both antimony sensitive and resistant Leishmania donovani clinical isolates in experimental infection.
BACKGROUND: In an endeavor to find an orally active and affordable antileishmanial drug, we tested the efficacy of a cationic amphiphilic drug, imipramine, commonly used for the treatment of depression in humans. The only available orally active antileishmanial drug is miltefosine with long half lif...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2012-01-01T00:00:00Z.
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