Serological responses and biomarker evaluation in mice and pigs exposed to tsetse fly bites.

• Main Authors: Guy Caljon (Author), Reta Duguma (Author), Reginald De Deken (Author), Stijn Schauvliege (Author), Frank Gasthuys (Author), Luc Duchateau (Author), Jan Van Den Abbeele (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Tsetse flies are obligate blood-feeding insects that transmit African trypanosomes responsible for human sleeping sickness and nagana in livestock. The tsetse salivary proteome contains a highly immunogenic family of the endonuclease-like Tsal proteins. In this study, a recombinant versi...