Legumain/pH dual-responsive lytic peptide-paclitaxel conjugate for synergistic cancer therapy

• Main Authors: Shanshan Zheng (Author), Yue Cai (Author), Yulu Hong (Author), Yubei Gong (Author), Licheng Gao (Author), Qingyong Li (Author), Le Li (Author), Xuanrong Sun (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

After molecule targeted drug, monoclonal antibody and antibody-drug conjugates (ADCs), peptide-drug conjugates (PDCs) have become the next generation targeted anti-tumor drugs due to its properties of low molecule weight, efficient cell penetration, low immunogenicity, good pharmacokinetic and large...