Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans

• Автори: Schalling Martin (Автор), Lonsdorf Tina B (Автор), Jensen Karin B (Автор), Kosek Eva (Автор), Ingvar Martin (Автор)
• Формат: Книга
• Опубліковано: SAGE Publishing, 2009-07-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>There is evidence from animal studies that serotonin (5-HT) can influence the antinociceptive effects of opioids at the spinal cord level. Therefore, there could be an influence of genetic polymorphisms in the serotonin system on ind...