Cytocidal Effect of Irradiation on Gastric Cancer Cells Infected with a Recombinant Mammalian Orthoreovirus Expressing a Membrane-Targeted KillerRed

• Main Authors: Yoshinori Shirasaka (Author), Kentaro Yamada (Author), Tsuyoshi Etoh (Author), Kazuko Noguchi (Author), Takumi Hasegawa (Author), Katsuhiro Ogawa (Author), Takeshi Kobayashi (Author), Akira Nishizono (Author), Masafumi Inomata (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The outcomes of unresectable gastric cancer (GC) are unfavorable even with chemotherapy; therefore, a new treatment modality is required. The combination of an oncolytic virus and photodynamic therapy can be one of the promising modalities to overcome this. Mammalian orthoreovirus (MRV) is an oncoly...