Synergistic Anti-Angiogenic Effects Using Peptide-Based Combinatorial Delivery of siRNAs Targeting VEGFA, VEGFR1, and Endoglin Genes

• Auteurs principaux: Anna A. Egorova (Auteur), Sofia V. Shtykalova (Auteur), Marianna A. Maretina (Auteur), Dmitry I. Sokolov (Auteur), Sergei A. Selkov (Auteur), Vladislav S. Baranov (Auteur), Anton V. Kiselev (Auteur)
• Format: Livre
• Publié: MDPI AG, 2019-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Angiogenesis is a process of new blood vessel formation, which plays a significant role in carcinogenesis and the development of diseases associated with pathological neovascularization. An important role in the regulation of angiogenesis belongs to several key pathways such as VEGF-pathways, TGF-&a...