Synergistic Anti-Angiogenic Effects Using Peptide-Based Combinatorial Delivery of siRNAs Targeting VEGFA, VEGFR1, and Endoglin Genes

• Main Authors: Anna A. Egorova (Author), Sofia V. Shtykalova (Author), Marianna A. Maretina (Author), Dmitry I. Sokolov (Author), Sergei A. Selkov (Author), Vladislav S. Baranov (Author), Anton V. Kiselev (Author)
• Format: Book
• Published: MDPI AG, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Angiogenesis is a process of new blood vessel formation, which plays a significant role in carcinogenesis and the development of diseases associated with pathological neovascularization. An important role in the regulation of angiogenesis belongs to several key pathways such as VEGF-pathways, TGF-&a...