Serum Creatinine and Serum Cystatin C are Both Relevant Renal Markers to Estimate Vancomycin Clearance in Critically Ill Neonates

• Main Authors: Stéphanie Leroux (Author), Valérie Biran (Author), John van den Anker (Author), Verena Gotta (Author), Wei Zhao (Author), Daolun Zhang (Author), Evelyne Jacqz-Aigrain (Author), Marc Pfister (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Serum creatinine (SCr) is used as a marker of kidney function to guide dosing of renally eliminated drugs. Serum Cystatin C (S-CysC) has been suggested as a more reliable kidney marker than SCr in adults and children. Purpose of this study was to investigate S-CysC as alternative renal mark...