Design, docking, MD simulation and in-silco ADMET prediction studies of novel indole-based benzamides targeting estrogen receptor alfa positive for effective breast cancer therapy

• Main Authors: Bhagyashri J. Warude (Author), Sandip N. Wagh (Author), Vivekanda A. Chatpalliwar (Author), Merve Yildirim (Author), Ismail Celik (Author), Mithun Rudrapal (Author), Johra Khan (Author), Sampath Chinnam (Author), Aniket A. Garud (Author), Vishnu S. Neharkar (Author)
• Format: Book
• Published: Pensoft Publishers, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breast cancer is one of the most common malignancies in women, afflicting millions of lives each year. Our current study suggests that the development of the most promising 7-substituted -1-(4-(piperidine-1-yl methoxy)benzyl)-1H-indole-3-carboxamide derivatives results in potent anticancer agents th...