Design, docking, MD simulation and in-silco ADMET prediction studies of novel indole-based benzamides targeting estrogen receptor alfa positive for effective breast cancer therapy

• मुख्य लेखकों: Bhagyashri J. Warude (लेखक), Sandip N. Wagh (लेखक), Vivekanda A. Chatpalliwar (लेखक), Merve Yildirim (लेखक), Ismail Celik (लेखक), Mithun Rudrapal (लेखक), Johra Khan (लेखक), Sampath Chinnam (लेखक), Aniket A. Garud (लेखक), Vishnu S. Neharkar (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Pensoft Publishers, 2023-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Breast cancer is one of the most common malignancies in women, afflicting millions of lives each year. Our current study suggests that the development of the most promising 7-substituted -1-(4-(piperidine-1-yl methoxy)benzyl)-1H-indole-3-carboxamide derivatives results in potent anticancer agents th...