Cigarette smoke promotes oral leukoplakia via regulating glutamine metabolism and M2 polarization of macrophage

• Main Authors: Yanan Zhu (Author), Shuo Zhang (Author), Jiahui Sun (Author), Tingting Wang (Author), Qin Liu (Author), Guanxi Wu (Author), Yajie Qian (Author), Weidong Yang (Author), Yong Wang (Author), Wenmei Wang (Author)
• Format: Book
• Published: Nature Publishing Group, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Oral immunosuppression caused by smoking creates a microenvironment to promote the occurrence and development of oral mucosa precancerous lesions. This study aimed to investigate the role of metabolism and macrophage polarization in cigarette-promoting oral leukoplakia. The effects of cigar...