Cardioprotective Effect of Nec-1 in Rats Subjected to MI/R: Downregulation of Autophagy-Like Cell Death

• Main Authors: Liang Wang (Author), Xuebai Lv (Author), Jue Tian (Author), Xiaoliang Wang (Author), Ye Wu (Author), Hui Rong Liu (Author)
• Format: Book
• Published: Hindawi-Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. Necrostatin-1 (Nec-1), an inhibitor of necroptosis, has been reported to protect against myocardial ischemia-reperfusion (MI/R) injury. However, the contribution of the potential antinecroptotic effect of Nec-1 on its infarct limitation and cardiac function improvement effects after MI/R...