Combination Therapy With Rapamycin and Low Dose Imatinib in Pulmonary Hypertension
Rationale: Enhanced proliferation and distal migration of human pulmonary arterial smooth muscle cells (hPASMCs) both contribute to the progressive increases in pulmonary vascular remodeling and resistance in pulmonary arterial hypertension (PAH). Our previous studies revealed that Rictor deletion,...
Saved in:
Main Authors: | Yinan Shi (Author), Chenxin Gu (Author), Tongtong Zhao (Author), Yangfan Jia (Author), Changlei Bao (Author), Ang Luo (Author), Qiang Guo (Author), Ying Han (Author), Jian Wang (Author), Stephen M. Black (Author), Ankit A. Desai (Author), Haiyang Tang (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2021-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Salusin-β, a TOR2A gene product, promotes proliferation, migration, fibrosis, and calcification of smooth muscle cells and accelerates the imbalance of vasomotor function and vascular remodeling in monocrotaline-induced pulmonary hypertensive rats
by: Xingxing Wang, et al.
Published: (2022) -
Donnan Potential across the Outer Membrane of Gram-Negative Bacteria and Its Effect on the Permeability of Antibiotics
by: Olaniyi Alegun, et al.
Published: (2021) -
Rapamycin maintains the primordial follicle pool and protects ovarian reserve against cyclophosphamide-induced damage
by: Xiuying CHEN, et al.
Published: (2022) -
CircRNA Microarray Profiling Reveals hsa_circ_0058493 as a Novel Biomarker for Imatinib-Resistant CML
by: An-Ni Zhong, et al.
Published: (2021) -
Rapamycin activates mammalian microautophagy
by: Masahiro Sato, et al.
Published: (2019)