Hereditary Systemic Autoinflammatory Diseases: Therapeutic Stratification

• المؤلفون الرئيسيون: Ovgu Kul Cinar (مؤلف), Amber Putland (مؤلف), Karen Wynne (مؤلف), Despina Eleftheriou (مؤلف), Paul A. Brogan (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Hereditary systemic autoinflammatory diseases (SAIDs) are rare, often severe conditions characterised by mutations in the key regulators of innate immune responses. Dramatic advances in the molecular genetics and next-generation sequencing in the past decade enabled identification of novel mutations...