Hereditary Systemic Autoinflammatory Diseases: Therapeutic Stratification

• Hauptverfasser: Ovgu Kul Cinar (Verfasst von), Amber Putland (Verfasst von), Karen Wynne (Verfasst von), Despina Eleftheriou (Verfasst von), Paul A. Brogan (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Hereditary systemic autoinflammatory diseases (SAIDs) are rare, often severe conditions characterised by mutations in the key regulators of innate immune responses. Dramatic advances in the molecular genetics and next-generation sequencing in the past decade enabled identification of novel mutations...