Hereditary Systemic Autoinflammatory Diseases: Therapeutic Stratification

• Main Authors: Ovgu Kul Cinar (Author), Amber Putland (Author), Karen Wynne (Author), Despina Eleftheriou (Author), Paul A. Brogan (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Hereditary systemic autoinflammatory diseases (SAIDs) are rare, often severe conditions characterised by mutations in the key regulators of innate immune responses. Dramatic advances in the molecular genetics and next-generation sequencing in the past decade enabled identification of novel mutations...