Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice

Attenuated secretion of glucose-dependent insulinotropic polypeptide (GIP) does not alleviate hyperphagic obesity and insulin resistance in ob/ob mice

Objective: Glucose-dependent insulinotropic polypeptide (GIP) is released during meals and promotes nutrient uptake and storage. GIP receptor knockout mice are protected from diet induced weight gain and thus GIP antagonists have been proposed as a treatment for obesity. In this study, we assessed t...

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Main Authors: Satoko Shimazu-Kuwahara (Author), Norio Harada (Author), Shunsuke Yamane (Author), Erina Joo (Author), Akiko Sankoda (Author), Timothy J. Kieffer (Author), Nobuya Inagaki (Author)
Format: Book
Published: Elsevier, 2017-03-01T00:00:00Z.
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3rd Floor Main Library

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