Gallic acid and metformin co-administration reduce oxidative stress, apoptosis and inflammation via Fas/caspase-3 and NF-κB signaling pathways in thioacetamide-induced acute hepatic encephalopathy in rats

Abstract Background Hepatic encephalopathy (HE) is a consequence of chronic or acute liver diseases. This study evaluates the combined effect of gallic acid (GA), and metformin (Met) on the liver and brain damage associated with HE. Methods Acute HE was induced by a single dose of thioacetamide (TAA...

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Autores principales: Ehsan Khedre Mohamed (Autor), Dawlat Mohamed Hafez (Autor)
Formato: Libro
Publicado: BMC, 2023-07-01T00:00:00Z.
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