Design and synthesis of a novel photoaffinity probe for labelling EGF receptor tyrosine kinases

• Egile Nagusiak: You-Guang Zheng (Egilea), Xiao-Qing Wu (Egilea), Jun Su (Egilea), Ping Jiang (Egilea), Liang Xu (Egilea), Jian Gao (Egilea), Bin Cai (Egilea), Min Ji (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The epidermal growth factor receptor (EGFR) and HER2 are two important tyrosine kinases that play crucial roles in signal transduction pathways that regulate numerous cellular functions including proliferation, differentiation, migration, and angiogenesis. In the past 20 years, many proteomic method...