Stereochemistry matters: Inhibition of carbonic anhydrase II by amino acid derived sulfamates depends on their absolute configuration

Aminoalcohols were converted into the corresponding enantiomeric phenylsulfonamide sulfamates. These compounds proved to be inhibitors of carbonic anhydrase II. Interestingly, a sulfamate derived from (S)-tryptophan was no inhibitor at all while its (R) configurated enantiomer was an excellent inhib...

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Main Authors: Toni C. Denner (Author), Elsa L. Klett (Author), Niels V. Heise (Author), René Csuk (Author)
Format: Book
Published: Elsevier, 2024-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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