Liquid Chromatography-Tandem Mass Spectrometry in Newborn Screening Laboratories

• Main Authors: Michael H. Gelb (Author), Khaja Basheeruddin (Author), Alberto Burlina (Author), Hsiao-Jan Chen (Author), Yin-Hsiu Chien (Author), George Dizikes (Author), Christine Dorley (Author), Roberto Giugliani (Author), Amy Hietala (Author), Xinying Hong (Author), Shu-Min Kao (Author), Hamid Khaledi (Author), Tracy Klug (Author), Francyne Kubaski (Author), Hsuan-Chieh Liao (Author), Monica Martin (Author), Adrienne Manning (Author), Joseph Orsini (Author), Yin Peng (Author), Enzo Ranieri (Author), Andreas Rohrwasser (Author), Nicolas Szabo-Fresnais (Author), Coleman T. Turgeon (Author), Frédérick M. Vaz (Author), Li-yun Wang (Author), Dietrich Matern (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS). Among the MS/MS applications in NBS, the most common is flow-injection analysis (FIA-) M...