RANK Deficiency Ameliorates Podocyte Injury by Suppressing Calcium/Calcineurin/ NFATc1 Signaling

• Main Authors: Shun Liang (Author), Hong Zhang (Author), Yue Du (Author), Caoshuai Dou (Author), Shuangxin Liu (Author), Li Zhang (Author), Yuanhan Chen (Author), Ruizhao Li (Author), Jianchao Ma (Author), Zhuo Li (Author), Ting Lin (Author), Xinchen Zhao (Author), Qianmei Zhang (Author), Wenjian Wang (Author), Zhiming Ye (Author), Xinling Liang (Author), Wei Shi (Author), Bin Zhang (Author)
• Format: Book
• Published: Karger Publishers, 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Podocyte injury and loss contribute to proteinuria, glomerulosclerosis and eventually kidney failure. Receptor activator of NF-κB (RANK) belongs to the TNF receptor superfamily, which plays a key role in the pathogenesis of podocyte injury. However, the mechanism underlying the effe...