Influence of probiotics on the periodontium, the oral microbiota and the immune response during orthodontic treatment in adolescent and adult patients (ProMB Trial): study protocol for a prospective, double-blind, controlled, randomized clinical trial

• Main Authors: Corinna L. Seidel (Author), Roman G. Gerlach (Author), Matthias Weider (Author), Theresa Wölfel (Author), Vincent Schwarz (Author), Armin Ströbel (Author), Helga Schmetzer (Author), Christian Bogdan (Author), Lina Gölz (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Orthodontic treatment with fixed appliances is often necessary to correct malocclusions in adolescence or adulthood. However, oral hygiene is complicated by appliances, and prior studies indicate that they may trigger oral inflammation and dysbiosis of the oral microbiota, especi...