Pharmacokinetics and Tissue Distribution of Enavogliflozin in Mice and Rats

• Main Authors: Minyeong Pang (Author), So Yeon Jeon (Author), Min-Koo Choi (Author), Ji-Hyeon Jeon (Author), Hye-Young Ji (Author), Ji-Soo Choi (Author), Im-Sook Song (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated the pharmacokinetics and tissue distribution of enavogliflozin, a novel sodium-glucose cotransporter 2 inhibitor that is currently in phase three clinical trials. Enavogliflozin showed dose-proportional pharmacokinetics following intravenous and oral administration (doses of...