Rapid and effective response of the R222Q SCN5A to quinidine treatment in a patient with Purkinje-related ventricular arrhythmia and familial dilated cardiomyopathy: a case report

• Main Authors: Joanna Zakrzewska-Koperska (Author), Maria Franaszczyk (Author), Zofia Bilińska (Author), Grażyna Truszkowska (Author), Małgorzata Karczmarz (Author), Łukasz Szumowski (Author), Tomasz Zieliński (Author), Rafał Płoski (Author), Maria Bilińska (Author)
• Format: Book
• Published: BMC, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mutations of the SCN5A gene are reported in 2-4% of patients with dilated cardiomyopathy (DCM). In such cases, DCM is associated with different rhythm disturbances such as the multifocal ectopic Purkinje-related premature contractions and atrial fibrillation. Arrhythmia often occ...