Astaxanthin Protects against Hyperglycemia-Induced Oxidative and Inflammatory Damage to Bone Marrow and to Bone Marrow-Retained Stem Cells and Restores Normal Hematopoiesis in Streptozotocin-Induced Diabetic Mice

• Main Authors: Govinda Bhattarai (Author), Han-Sol So (Author), Tae-Geum Kim (Author), Thi Thu Trang Kieu (Author), Yeon-Woo Kim (Author), Ku-Ri Yang (Author), Jeong-Chae Lee (Author), Sung-Ho Kook (Author), Young-Mi Jeon (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hyperglycemia has various adverse health effects, some of which are due to chronic oxidative and inflammatory impairment of bone marrow (BM), hematopoietic stem cells (HSCs), and mesenchymal stem cells (MSCs). Astaxanthin (ASTX) has been shown to ameliorate hyperglycemia-associated systemic complica...