Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function

• Main Authors: Jennifer L. Schwedler (Author), Maxwell A. Stefan (Author), Christine E. Thatcher (Author), Peter R. McIlroy (Author), Anupama Sinha (Author), Ashlee M. Phillips (Author), Christopher A. Sumner (Author), Colleen M. Courtney (Author), Christina Y. Kim (Author), Dina R. Weilhammer (Author), Brooke Harmon (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTThe development of specific, safe, and potent monoclonal antibodies (Abs) has led to novel therapeutic options for infectious disease. In addition to preventing viral infection through neutralization, Abs can clear infected cells and induce immunomodulatory functions through engagement of th...