Neural Differentiation in HDAC1-Depleted Cells Is Accompanied by Coilin Downregulation and the Accumulation of Cajal Bodies in Nucleoli

• Huvudskapare: Jana Krejčí (Författare, medförfattare), Soňa Legartová (Författare, medförfattare), Eva Bártová (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Hindawi Limited, 2017-01-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Cajal bodies (CBs) are important compartments containing accumulated proteins that preferentially regulate RNA-related nuclear events, including splicing. Here, we studied the nuclear distribution pattern of CBs in neurogenesis. In adult brains, coilin was present at a high density, but CB formation...