Mechanistic insights into ASO-RNA complexation: Advancing antisense oligonucleotide design strategies

Oligonucleotide drugs, an emerging modulator class, hold promise for targeting previously undruggable biomacromolecules. To date, only 18 oligonucleotide drugs, including sought-after antisense oligonucleotides (ASOs) and splice-switching oligonucleotides, have approval from the U.S. Food and Drug A...

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Main Authors: Johanna Hörberg (Author), Antonio Carlesso (Author), Anna Reymer (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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