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24-Hydroxycholesterol Induces Tau Proteasome-Dependent Degradation via the SIRT1/PGC1α/Nrf2 Pathway: A Potential Mechanism to Counteract Alzheimer's Disease

Considerable evidence indicates that cholesterol oxidation products, named oxysterols, play a key role in several events involved in Alzheimer's disease (AD) pathogenesis. Although the majority of oxysterols causes neuron dysfunction and degeneration, 24-hydroxycholesterol (24-OHC) has recently...

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Main Authors:	Gabriella Testa (Author), Serena Giannelli (Author), Barbara Sottero (Author), Erica Staurenghi (Author), Giorgio Giaccone (Author), Paola Caroppo (Author), Paola Gamba (Author), Gabriella Leonarduzzi (Author)
Format:	Book
Published:	MDPI AG, 2023-03-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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