Evaluation of machine learning methods for covariate data imputation in pharmacometrics

Abstract Missing data create challenges in clinical research because they lead to loss of statistical power and potentially to biased results. Missing covariate data must be handled with suitable approaches to prepare datasets for pharmacometric analyses, such as population pharmacokinetic and pharm...

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Main Authors: Dominic Stefan Bräm (Author), Uri Nahum (Author), Andrew Atkinson (Author), Gilbert Koch (Author), Marc Pfister (Author)
Format: Book
Published: Wiley, 2022-12-01T00:00:00Z.
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